Phenotypes Associated with This Genotype

Genotype
MGI:5757006

• Allelic Composition: Dnase1l2^{tm1.1(KOMP)Wtsi}/Dnase1l2^{tm1.1(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Dnase1l2^{tm1.1(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0296_2_A10

Data Sources

IMPC Data for Dnase1l2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

IMPC - UCD

increased total body fat amount ( J:211773 )

♂

IMPC - WTSI

behavior/neurological

decreased grip strength ( J:211773 )

♂

IMPC - WTSI

cardiovascular system

eye hemorrhage ( J:211773 )

♂

IMPC - UCD

growth/size/body

decreased lean body mass ( J:211773 )

♂

IMPC - WTSI

decreased body length ( J:211773 )

IMPC - WTSI

homeostasis/metabolism

increased circulating aspartate transaminase level ( J:211773 )

♀

IMPC - WTSI

limbs/digits/tail

abnormal digit morphology ( J:211773 )

♂

IMPC - WTSI

abnormal tibia morphology ( J:211773 )

IMPC - WTSI

short tibia ( J:211773 )

IMPC - UCD

abnormal tail morphology ( J:211773 )

IMPC - WTSI

skeleton

abnormal tibia morphology ( J:211773 )

IMPC - WTSI

short tibia ( J:211773 )

IMPC - UCD

abnormal spine curvature ( J:211773 )

♂

IMPC - WTSI

abnormal bone structure ( J:211773 )

♀

IMPC - UCD

decreased bone mineral content ( J:211773 )

IMPC - WTSI

abnormal joint morphology ( J:211773 )

♀

IMPC - WTSI

fusion of vertebral arches ( J:211773 )

♂

IMPC - WTSI

vision/eye

eye hemorrhage ( J:211773 )

♂

IMPC - UCD