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Phenotypes Associated with This Genotype
Genotype
MGI:5705592
Allelic
Composition
Tg(ITGAM-cre/ERT2,U6-RNAi:Cacna1b)17Ttan/0
Genetic
Background
C57BL/6J-Tg(ITGAM-cre/ERT2,U6-RNAi:Cacna1b)17Ttan
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(ITGAM-cre/ERT2,U6-RNAi:Cacna1b)17Ttan mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• following sciatic nerve ligation, tamoxifen-treated mice exhibit alleviated tactile allodynia and reduced accumulation of spinal microglia compared with control mice

behavior/neurological
N
• mice exhibit almost normal thermal hyperalgesia


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory