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Phenotypes Associated with This Genotype
Genotype
MGI:5702939
Allelic
Composition		 Cd44tm1Hbg/Cd44+
Tnftm2Gkl/Tnf+
Genetic
Background		 involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd44tm1Hbg mutation (4 available); any Cd44 mutation (74 available)
Tnftm2Gkl mutation (1 available); any Tnf mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
ileum inflammation ( J:145626 )
• reduced ileitis compared with Tnftm2Gkl heterozygous mice

immune system
ileum inflammation ( J:145626 )
• reduced ileitis compared with Tnftm2Gkl heterozygous mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory