About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5702481
Allelic
Composition		 Mapttm2Arbr/?
Runx1tm3Spe/Runx1tm3Spe
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
Mapttm2Arbr mutation (1 available); any Mapt mutation (453 available)
Runx1tm3Spe mutation (0 available); any Runx1 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal sensory neuron innervation pattern ( J:226826 )
• reduction of sensory innervtion of the epidermic at P0
abnormal axon morphology ( J:226826 )
• reduction in epidermal nerve fiber density

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory