Phenotypes Associated with This Genotype

Genotype
MGI:5702449

• Allelic Composition: Ntn5^tm1.1Rwb/Ntn5^tm1.1Rwb
• Genetic Background: STOCK Ntn5^tm1.1Rwb/Rwb

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:227617 )

N • boundary cap cells are present, and there are no abnormalities in cranial nerve guidance, dorsal root organization, sensory projections, and no nociceptive defects were detected by either von Frey or hot plate testing

ectopic neuron ( J:227617 )

• homozygotes have ectopic motor neurons that migrate out of the ventral horn and into the motor roots, with more ectopias in the rostral than the caudal end, and these ectopic neurons do not express neuropilin 2

behavior/neurological

behavior/neurological phenotype ( J:227617 )

N • grip strength, gait, and general motor activity, including characterization in the Knockout Mouse Phenotyping (KOMP2) project, are all normal