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Phenotypes Associated with This Genotype
Genotype
MGI:5702406
Allelic
Composition		 Acacatm1Dejs/Acacatm1Dejs
Tg(Cd4-cre)1Cwi/?
Tg(TcraTcrb)1100Mjb/?
Genetic
Background		 involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Acacatm1Dejs mutation (2 available); any Acaca mutation (126 available)
Tg(Cd4-cre)1Cwi mutation (12 available)
Tg(TcraTcrb)1100Mjb mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased T cell proliferation ( J:209886 )
• significant CD8+ T cell expansion after Listeria-OVA exposure
• cell survival is reduced

hematopoietic system
increased T cell proliferation ( J:209886 )
• significant CD8+ T cell expansion after Listeria-OVA exposure
• cell survival is reduced

cellular
increased T cell proliferation ( J:209886 )
• significant CD8+ T cell expansion after Listeria-OVA exposure
• cell survival is reduced

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory