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Phenotypes Associated with This Genotype
Genotype
MGI:5699438
Allelic
Composition		 Eomestm1.1Twa/?
Tg(CD2-Tbx21)#Staka/?
Genetic
Background		 involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eomestm1.1Twa mutation (1 available); any Eomes mutation (42 available)
Tg(CD2-Tbx21)#Staka mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal NK cell differentiation ( J:210160 )
• large populations of Eomes- NK cells
• decrease in all populations of Eomes+ NK cells

hematopoietic system
abnormal NK cell differentiation ( J:210160 )
• large populations of Eomes- NK cells
• decrease in all populations of Eomes+ NK cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory