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Phenotypes Associated with This Genotype
Genotype
MGI:5699436
Allelic
Composition		 Eomestm1.1Twa/?
Tg(Itgax-TGFBR2)1Flv/?
Genetic
Background		 involves: C3H * C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eomestm1.1Twa mutation (1 available); any Eomes mutation (42 available)
Tg(Itgax-TGFBR2)1Flv mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal NK cell differentiation ( J:210160 )
• no effect on Eomes- NK cells
• Eomes+ NK cell number is increased

hematopoietic system
abnormal NK cell differentiation ( J:210160 )
• no effect on Eomes- NK cells
• Eomes+ NK cell number is increased

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory