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Phenotypes Associated with This Genotype
Genotype
MGI:5697722
Allelic
Composition		 Ccnctm1.1Pisc/Ccnctm1.1Pisc
Tg(Lck-LMO1)11Sjk/0
Tg(Mx1-cre)1Cgn/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccnctm1.1Pisc mutation (0 available); any Ccnc mutation (25 available)
Tg(Lck-LMO1)11Sjk mutation (0 available)
Tg(Mx1-cre)1Cgn mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased T cell derived lymphoma incidence ( J:217695 )
• strongly increased tumour incidence of T-ALL with elevated ICN1 levels in mutant tumors

endocrine/exocrine glands
increased T cell derived lymphoma incidence ( J:217695 )
• strongly increased tumour incidence of T-ALL with elevated ICN1 levels in mutant tumors

immune system
increased T cell derived lymphoma incidence ( J:217695 )
• strongly increased tumour incidence of T-ALL with elevated ICN1 levels in mutant tumors

hematopoietic system
increased T cell derived lymphoma incidence ( J:217695 )
• strongly increased tumour incidence of T-ALL with elevated ICN1 levels in mutant tumors

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory