About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5696542
Allelic
Composition		 Atg16l1tm1c(EUCOMM)Wtsi/Atg16l1tm1c(EUCOMM)Wtsi
Tg(Itgax-cre)1-1Reiz/?
Genetic
Background		 involves: C57BL/6 * C57BL/6N * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atg16l1tm1c(EUCOMM)Wtsi mutation (0 available); any Atg16l1 mutation (44 available)
Tg(Itgax-cre)1-1Reiz mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
cellular phenotype ( J:221019 )
N
• normal up-regulation of expression of autophagy regulators in intestinal epithelia, the mesenchymal compartment, and in cecal patches after infection with Salmonella typhimurium as seen in controls

immune system
immune system phenotype ( J:221019 )
N
• normal cytokine response by intestinal epithelial cells to infection

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory