Phenotypes Associated with This Genotype

Genotype
MGI:5696327

• Allelic Composition: Gipc1^tm1.1Mhsi/Gipc1^tm1.1Mhsi; Tg(Tek-cre)12Flv/?
• Genetic Background: involves: 129S1/SvImJ * 129S4/SvJaeSor * C3H * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal systemic artery morphology ( J:221554 )

• less arterial branching and fewer collateral arteries in heart and kidney

• significant decrease in smaller arteries

• fewer arteriolar linkages in the spinotrapezius and a more dendritic arterial tree

• narrower input arterioles

coronary artery aneurysm ( J:221554 )

• aneurismal dilations in distal coronary arteries

abnormal blood circulation ( J:221554 )

• impaired recovery of blood flow after hind limb ischemia