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Phenotypes Associated with This Genotype
Genotype
MGI:5691376
Allelic
Composition		 Bak1tm1Thsn/Bak1tm1Thsn
Baxtm2Sjk/Baxtm2Sjk
Tg(Lck-cre)1Cwi/?
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bak1tm1Thsn mutation (2 available); any Bak1 mutation (26 available)
Baxtm2Sjk mutation (1 available); any Bax mutation (24 available)
Tg(Lck-cre)1Cwi mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased thymocyte apoptosis ( J:220951 )
• completely resistant to apoptosis

cellular
decreased thymocyte apoptosis ( J:220951 )
• completely resistant to apoptosis

hematopoietic system
decreased thymocyte apoptosis ( J:220951 )
• completely resistant to apoptosis

endocrine/exocrine glands
decreased thymocyte apoptosis ( J:220951 )
• completely resistant to apoptosis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory