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Phenotypes Associated with This Genotype
Genotype
MGI:5691375
Allelic
Composition		 Vdac2tm1.1Ehyc/Vdac2tm1.1Ehyc
Baxtm2Sjk/Baxtm2Sjk
Tg(Lck-cre)1Cwi/?
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Baxtm2Sjk mutation (1 available); any Bax mutation (24 available)
Tg(Lck-cre)1Cwi mutation (3 available)
Vdac2tm1.1Ehyc mutation (0 available); any Vdac2 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased thymocyte number ( J:220951 )
• two fold reduction of thymocytes although the developmental profile seems normal

hematopoietic system
decreased thymocyte number ( J:220951 )
• two fold reduction of thymocytes although the developmental profile seems normal

endocrine/exocrine glands
decreased thymocyte number ( J:220951 )
• two fold reduction of thymocytes although the developmental profile seems normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory