Analysis Tools
immune system
|
• BAK from T cells is more sensitive to apoptotic signals
• earlier translocation of cytochrome c out of mitochondria
• earlier caspase activation
• thymocytes cultured with antibody to CD3 die more rapidly
|
small thymus
(
J:220951
)
|
• further shrinkage of thymus when mice injected with antibody to CD3
|
|
• two fold reduction of thymocytes although the developmental profile seems normal
• 90% of double+ thymocytes killed when mice injected with antibody to CD3
|
cellular
|
• BAK from T cells is more sensitive to apoptotic signals
• earlier translocation of cytochrome c out of mitochondria
• earlier caspase activation
• thymocytes cultured with antibody to CD3 die more rapidly
|
hematopoietic system
|
• BAK from T cells is more sensitive to apoptotic signals
• earlier translocation of cytochrome c out of mitochondria
• earlier caspase activation
• thymocytes cultured with antibody to CD3 die more rapidly
|
small thymus
(
J:220951
)
|
• further shrinkage of thymus when mice injected with antibody to CD3
|
|
• two fold reduction of thymocytes although the developmental profile seems normal
• 90% of double+ thymocytes killed when mice injected with antibody to CD3
|
endocrine/exocrine glands
|
• BAK from T cells is more sensitive to apoptotic signals
• earlier translocation of cytochrome c out of mitochondria
• earlier caspase activation
• thymocytes cultured with antibody to CD3 die more rapidly
|
small thymus
(
J:220951
)
|
• further shrinkage of thymus when mice injected with antibody to CD3
|
|
• two fold reduction of thymocytes although the developmental profile seems normal
• 90% of double+ thymocytes killed when mice injected with antibody to CD3
|
