Phenotypes for Gt(ROSA)26Sor Tfrc Tg(Vil1-cre)20Syr MGI:5689324 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^{tm1(Tfrc*)Nca}/Gt(ROSA)26Sor⁺ Tfrc^tm3.1Nca/Tfrc^tm3.1Nca Tg(Vil1-cre)20Syr/0
Genetic Background	involves: 129S4/SvJae * C57BL/6 * CD-1 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm1(Tfrc*)Nca} mutation (1 available); any Gt(ROSA)26Sor mutation (945 available)
Tfrc^tm3.1Nca mutation (2 available); any Tfrc mutation (61 available)
Tg(Vil1-cre)20Syr mutation (3 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:224823 )

• some mice die postnatally

• however, most mice are alive at 2 months

digestive/alimentary system

abnormal digestive system morphology ( J:224823 )

• mice that die exhibit the same phenotype as Tfrc^tm3.1Nca/Tfrc^tm3.1Nca Tg(Vil-cre)20Syr mice

• however, mice that survive at 2 months exhibit normal architecture and proliferation of crypt intestinal epithelial cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/21/2024 MGI 6.23