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Phenotypes Associated with This Genotype
Genotype
MGI:5688516
Allelic
Composition		 Trp53tm1Tyj/Trp53tm1Tyj
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (232 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased mortality induced by ionizing radiation ( J:216929 )
• median survival following exposure to 8 gray of whole body gamma-irradiation is 34 days
premature death ( J:216929 )
• longest lifespan is 34 weeks, median survival is 25 weeks

homeostasis/metabolism
decreased mortality induced by ionizing radiation ( J:216929 )
• median survival following exposure to 8 gray of whole body gamma-irradiation is 34 days

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory