Phenotypes Associated with This Genotype

Genotype
MGI:5659953

• Allelic Composition: Srf^tm1Rmn/Srf^tm1Rmn; H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * CBA/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:144862 )

• mice die at late embryonic stages

craniofacial

craniofacial phenotype ( J:144862 )

N • tongue is present

mandible hypoplasia ( J:144862 )

cardiovascular system

persistent truncus arteriosus ( J:144862 )

ventricular septal defect ( J:144862 )

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:144862 )

N • external ear is present

immune system

athymia ( J:144862 )

skeleton

mandible hypoplasia ( J:144862 )

hematopoietic system

athymia ( J:144862 )

endocrine/exocrine glands

athymia ( J:144862 )

absent thyroid gland ( J:144862 )

growth/size/body

mandible hypoplasia ( J:144862 )