Phenotypes Associated with This Genotype

Genotype
MGI:5659952

• Allelic Composition: Map2k1^tm1Chrn/Map2k1^tm1Chrn; Map2k2^tm1Chrn/Map2k2^tm1Chrn; H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
• Genetic Background: involves: 129/Sv * C57BL/6J * CBA/J * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

mandible hypoplasia ( J:144862 )

• at E17.5

short maxilla ( J:144862 )

• at E17.5

absent tongue ( J:144862 )

abnormal outer ear morphology ( J:144862 )

cardiovascular system

persistent truncus arteriosus ( J:144862 )

• at E16.5 and E17.5

hearing/vestibular/ear

abnormal outer ear morphology ( J:144862 )

growth/size/body

mandible hypoplasia ( J:144862 )

• at E17.5

short maxilla ( J:144862 )

• at E17.5

absent tongue ( J:144862 )

abnormal outer ear morphology ( J:144862 )

digestive/alimentary system

absent tongue ( J:144862 )

skeleton

mandible hypoplasia ( J:144862 )

• at E17.5

short maxilla ( J:144862 )

• at E17.5

vision/eye

abnormal eye distance/ position ( J:144862 )