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Phenotypes Associated with This Genotype
Genotype
MGI:5639333
Allelic
Composition		 Gt(ROSA)26Sortm1(cre/ERT2)Thl/0
Picalmtm1.1Tmae/Picalmtm1.1Tmae
Genetic
Background		 involves: 129 * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(cre/ERT2)Thl mutation (0 available); any Gt(ROSA)26Sor mutation (1062 available)
Picalmtm1.1Tmae mutation (1 available); any Picalm mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal erythropoiesis ( J:220728 )
• inefficient erythroid differentiation in the spleen following tamoxifen treatment
hypochromic microcytic anemia ( J:220728 )
• mice develop microcytic and hypochromic anemia following tamoxifen treatment

integument
diluted coat color ( J:220728 )
• gray coat color

pigmentation
diluted coat color ( J:220728 )
• gray coat color

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory