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Phenotypes Associated with This Genotype
Genotype
MGI:5636670
Allelic
Composition		 ApcMin/Apc+
Msh2tm1Mak/Msh2tm1Mak
Nos2tm1Mrl/Nos2tm1Mrl
Genetic
Background		 involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ApcMin mutation (12 available); any Apc mutation (151 available)
Msh2tm1Mak mutation (1 available); any Msh2 mutation (95 available)
Nos2tm1Mrl mutation (6 available); any Nos2 mutation (70 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
intestine polyps ( J:200824 )
• mutants exhibit similar polyp formation in the small intestine and colon as mice heterozygous for ApcMin and homozygous for Msh2tm1Mak

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory