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Phenotypes Associated with This Genotype
Genotype
MGI:5635894
Allelic
Composition
Idh1tm3Mak/Idh1+
Tg(Col2a1-cre/ERT2)1Dic/0
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Idh1tm3Mak mutation (0 available); any Idh1 mutation (40 available)
Tg(Col2a1-cre/ERT2)1Dic mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• mice injected with tamoxifen at 4 weeks of age for 10 doses exhibit knees with multiple enchondroma-like cartilage lesions adjacent to the growth plates; 4-8 cartilage lesions are seen in the growth plates of each knee


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory