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Phenotypes Associated with This Genotype
Genotype
MGI:5609590
Allelic
Composition		 Mc4rtm2Lowl/Mc4rtm2Lowl
Tg(Sim1-cre)1Lowl/0
Genetic
Background		 involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mc4rtm2Lowl mutation (0 available); any Mc4r mutation (44 available)
Tg(Sim1-cre)1Lowl mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
adipose tissue
increased total body fat amount ( J:216397 )
• increase in fat mass

behavior/neurological

growth/size/body
obese ( J:216397 )
increased body length ( J:216397 )

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory