Phenotypes for Lman1 Tg(Tek-cre)12Flv MGI:5607596 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Lman1^{tm1c(KOMP)Wtsi}/Lman1^{tm1c(KOMP)Wtsi} Tg(Tek-cre)12Flv/0
Genetic Background	involves: C57BL/6 * C57BL/6J * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lman1^{tm1c(KOMP)Wtsi} mutation (0 available); any Lman1 mutation (22 available)
Tg(Tek-cre)12Flv mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

abnormal blood homeostasis ( J:213133 )

• mice show a reduction in plasma coagulation factor VIII (FVIII) activity levels

• however plasma coagulation factor V (FV) activity is normal

hematopoietic system

abnormal platelet morphology ( J:213133 )

• modest reduction in platelet FV antigen

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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