About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5604875
Allelic
Composition		 Pepddal/Pepddal
Tg(Myh6*/tetO-GCaMP2)1Mik/0
Genetic
Background		 involves: C3H/HeJ * C57BL/6J * CBA/J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pepddal mutation (1 available); any Pepd mutation (35 available)
Tg(Myh6*/tetO-GCaMP2)1Mik mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal fetal cardiomyocyte physiology ( J:215150 )
• 43% of E12.5 dark-like homozygotes display abnormal calcium transients such as early after-depolarizations and interval irregularities, and those hearts that have these abnormalities also have thickened ventricular walls whereas those not displaying irregularities in calcium handling appeared normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory