Phenotypes Associated with This Genotype

Genotype
MGI:5604446

• Allelic Composition: Tg(Mdm2)1Snj/0
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased tumor incidence ( J:51661 )

• 50% of mice succumb to neoplasia by 84 weeks of age

increased pituitary adenoma incidence ( J:51661 )

• 1 of 16 tumors are pituitary adenomas

increased lymphoma incidence ( J:51661 )

• 64% tumors are malignant lymphoma

increased adenocarcinoma incidence ( J:51661 )

• 1 of 16 tumors are adenocarcinomas

increased sarcoma incidence ( J:51661 )

• 38% of all tumors seen in mice are sarcomas

increased rhabdomyosarcoma incidence ( J:51661 )

• 1 of 16 tumors are rhabdomyosarcomas

increased hemangiosarcoma incidence ( J:51661 )

• 9 of 26 tumors are hemangiosarcomas

endocrine/exocrine glands

increased pituitary adenoma incidence ( J:51661 )

• 1 of 16 tumors are pituitary adenomas

muscle

increased rhabdomyosarcoma incidence ( J:51661 )

• 1 of 16 tumors are rhabdomyosarcomas

nervous system

increased pituitary adenoma incidence ( J:51661 )

• 1 of 16 tumors are pituitary adenomas