Phenotypes Associated with This Genotype

Genotype
MGI:5588435

• Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/Gt(ROSA)26Sor^{tm1(Grem1)Svok}
• Genetic Background: involves: 129S1/Sv * 129S4/SvJae

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

abnormal digit morphology ( J:214075 )

• following tamoxifen administration at E9.5, hindlimb digits exhibit nubs (ectopic pieces of cartilage (7/12)

• following tamoxifen administration at E10.5, hindlimb digits exhibit nubs (5/5

• following tamoxifen administration at E9.5 and E10.5, all forelimb digits exhibit nubs

• following tamoxifen administration at E11.5, some forelimb digits exhibit nubs (3/5)

• following tamoxifen administraion, hindlimbs and forelimbs do not form nubs or polydactyly after E11.5

polydactyly ( J:214075 )

• following tamoxifen administration at E9.5, hindlimb digits exhibit polydactyly (5/12)

• following tamoxifen administration, hindlimbs and forelimbs do not form nubs or polydactyly after E11.5