Phenotypes for Egr2 Gt(ROSA)26Sor Ptpn11 MGI:5588145 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Egr2^tm2(cre)Pch/Egr2⁺ Gt(ROSA)26Sor^{tm8(Map2k1*,-EGFP)Rsky}/? Ptpn11^tm1.1Wbm/Ptpn11^tm1.1Wbm
Genetic Background	involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Egr2^tm2(cre)Pch mutation (2 available); any Egr2 mutation (32 available)
Gt(ROSA)26Sor^{tm8(Map2k1*,-EGFP)Rsky} mutation (1 available); any Gt(ROSA)26Sor mutation (1062 available)
Ptpn11^tm1.1Wbm mutation (1 available); any Ptpn11 mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

hypermyelination ( J:207470 )

• mice show normal myelination at P15, however axons of peripheral nerves are hypermyelinated by P90

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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