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Phenotypes Associated with This Genotype
Genotype
MGI:5585152
Allelic
Composition		 Agtr1atm1Unc/Agtr1atm1Unc
Efemp2tm1.1Hiya/Efemp2tm1.2Hiya
Tg(Tagln-cre)1Her/0
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agtr1atm1Unc mutation (1 available); any Agtr1a mutation (38 available)
Efemp2tm1.1Hiya mutation (0 available); any Efemp2 mutation (26 available)
Efemp2tm1.2Hiya mutation (0 available); any Efemp2 mutation (26 available)
Tg(Tagln-cre)1Her mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
increased aorta wall thickness ( J:213282 )
• aortic wall is thicker at 3 months of age compared to single Agtr1a homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory