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Phenotypes Associated with This Genotype
Genotype
MGI:5577180
Allelic
Composition		 Mnd1Gt(RRS590)Byg/Mnd1Gt(RRS590)Byg
Psmc3iptm1Rdco/Psmc3iptm1Rdco
Genetic
Background		 involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mnd1Gt(RRS590)Byg mutation (0 available); any Mnd1 mutation (12 available)
Psmc3iptm1Rdco mutation (0 available); any Psmc3ip mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal male meiosis ( J:207221 )
• homologous chromosomes fails to synapse in some cases

cellular
abnormal male meiosis ( J:207221 )
• homologous chromosomes fails to synapse in some cases
impaired double-strand DNA break repair ( J:207221 )
• defects in double-strand break repair

homeostasis/metabolism
impaired double-strand DNA break repair ( J:207221 )
• defects in double-strand break repair

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory