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Phenotypes Associated with This Genotype
Genotype
MGI:5576521
Allelic
Composition		 Ctnnb1tm1Mmt/Ctnnb1+
Tg(Wap-cre)11738Mam/0
Genetic
Background		 FVB.Cg-Ctnnb1tm1Mmt Tg(Wap-cre)11738Mam
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1tm1Mmt mutation (0 available); any Ctnnb1 mutation (47 available)
Tg(Wap-cre)11738Mam mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased mammary gland tumor incidence in breeding females ( J:206839 )
• the majority of females develop mammary gland tumors between 25 and 40 weeks postpartum
• tumors are squamous metaplasia

endocrine/exocrine glands
increased mammary gland tumor incidence in breeding females ( J:206839 )
• the majority of females develop mammary gland tumors between 25 and 40 weeks postpartum
• tumors are squamous metaplasia

integument
increased mammary gland tumor incidence in breeding females ( J:206839 )
• the majority of females develop mammary gland tumors between 25 and 40 weeks postpartum
• tumors are squamous metaplasia

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory