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Phenotypes Associated with This Genotype
Genotype
MGI:5568837
Allelic
Composition
Iqgap2tm1Vs/Iqgap2tm1Vs
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Iqgap2tm1Vs mutation (1 available); any Iqgap2 mutation (55 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
liver/biliary system
• mice develop hepatocellular carcinoma that recapitulates molecular features of advanced human hepatocellular carcinoma

neoplasm
• mice develop hepatocellular carcinoma that recapitulates molecular features of advanced human hepatocellular carcinoma

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
hepatocellular carcinoma DOID:684 OMIM:114550
J:205882


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory