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Phenotypes Associated with This Genotype
Genotype
MGI:5568090
Allelic
Composition
Npr2tm1Fgr/Npr2tm1Fgr
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Npr2tm1Fgr mutation (0 available); any Npr2 mutation (63 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• at P56 mice display significantly reduced body size due to impaired endochondral ossification, as described for other mutants like Npr2tm1Gar and Npr2cn homozygotes

nervous system
• at E12.5 the trigeminal funiculus is reduced in size
• animals lack bifurcation of DRG axons at the dorsal root entry zone


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory