Phenotypes for Gt(ROSA)26Sor Hprt1 Tg(Ins2-cre/ERT)1Dam MGI:5567828 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor⁺ Hprt1^{tm1(Ins2-HBEGF)Herr}/Y Tg(Ins2-cre/ERT)1Dam/0
Genetic Background	involves: 129X1/SvJ * C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^tm1(EYFP)Cos mutation (24 available); any Gt(ROSA)26Sor mutation (1062 available)
Hprt1^{tm1(Ins2-HBEGF)Herr} mutation (0 available); any Hprt1 mutation (1280 available)
Tg(Ins2-cre/ERT)1Dam mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:159291 )

N	• spared beta cells in diphtheria- and tamoxifen-treated mice do not exhibit increased replication

abnormal pancreatic islet morphology ( J:159291 )

• bihormonal (glucagon+ and insulin+) cells arise in the islets of diphtheria-treated mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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