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Phenotypes Associated with This Genotype
Genotype
MGI:5562293
Allelic
Composition		 Cd274tm1Igu/Cd274+
Genetic
Background		 involves: 129 * C57BL/6 * CBA/CaJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd274tm1Igu mutation (0 available); any Cd274 mutation (72 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality throughout fetal growth and development, incomplete penetrance ( J:100544 )
• when homozygous females on a 129 and C57BL/6 background are mated to wild-type males on a CBA/CaJ background, a reduction in heterozygous fetal survival rates is seen

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory