Phenotypes for Mirc31 Tg(Vil1-cre)997Gum MGI:5560214 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mirc31^tm1.1Aru/Mirc31^tm1.1Aru Tg(Vil1-cre)997Gum/0
Genetic Background	involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mirc31^tm1.1Aru mutation (0 available); any Mirc31 mutation (2 available)
Tg(Vil1-cre)997Gum mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

digestive/alimentary system

abnormal intestine morphology ( J:202923 )

• modest but significant intestinal hypertrophy

abnormal crypts of Lieberkuhn morphology ( J:202923 )

• increase in the fraction of fissile crypts

abnormal small intestine morphology ( J:202923 )

• thicker

decreased Paneth cell number ( J:202923 )

• modest decrease in the number of Paneth cells

endocrine/exocrine glands

abnormal crypts of Lieberkuhn morphology ( J:202923 )

• increase in the fraction of fissile crypts

decreased Paneth cell number ( J:202923 )

• modest decrease in the number of Paneth cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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