Phenotypes Associated with This Genotype

Genotype
MGI:5560158

• Allelic Composition: b2b2362Clo/b2b2362Clo
• Genetic Background: C57BL/6J-b2b2362Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 2362-004-1 (E16.5) exhibits ectopia cordis, ventricular non-compaction, and gastroschisis with a body wall closure defect

cardiovascular system

myocardial hypertrabeculation ( J:175213 )

• Excessive myocardial trabeculation or noncompaction

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

double outlet right ventricle with atrioventricular septal defect ( J:175213 )

double outlet right ventricle, Taussig bing type ( J:175213 )

ectopia cordis ( J:175213 )

ventricular septal defect ( J:175213 )

craniofacial

micrognathia ( J:175213 )

cleft upper lip ( J:175213 )

cleft palate ( J:175213 )

short snout ( J:175213 )

facial cleft ( J:175213 )

abnormal head shape ( J:175213 )

• dome shaped head

digestive/alimentary system

cleft palate ( J:175213 )

growth/size/body

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

micrognathia ( J:175213 )

cleft upper lip ( J:175213 )

cleft palate ( J:175213 )

short snout ( J:175213 )

facial cleft ( J:175213 )

abnormal head shape ( J:175213 )

• dome shaped head

herniated abdominal wall ( J:175213 )

renal glomerulus cyst ( J:175213 )

muscle

myocardial hypertrabeculation ( J:175213 )

• Excessive myocardial trabeculation or noncompaction

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

skeleton

micrognathia ( J:175213 )

renal/urinary system

renal glomerulus cyst ( J:175213 )

renal hypoplasia ( J:175213 )