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Phenotypes Associated with This Genotype
Genotype
MGI:5556199
Allelic
Composition		 Elntm1Dyl/Eln+
Mgptm1Kry/Mgptm1Kry
Genetic
Background		 involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elntm1Dyl mutation (0 available); any Eln mutation (41 available)
Mgptm1Kry mutation (1 available); any Mgp mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
calcified artery ( J:203924 )
• progression of arterial calcification is delayed compared to single Mgp homozygotes

skeleton
abnormal epiphyseal plate morphology ( J:203924 )
• vertebral growth plates are abnormally calcified
• however, bone volume, trabecular and cortical bone mass, osteoblast and osteoclast counts, and bone formation are normal at 5 weeks of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory