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Phenotypes Associated with This Genotype
Genotype
MGI:5555860
Allelic
Composition		 Col1a1tm1(tetO-Fos)Wag/Col1a1+
Rag1tm1Mom/Rag1tm1Mom
Tg(KRT5-rtTA)T2D6Sgkd/0
Genetic
Background		 involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col1a1tm1(tetO-Fos)Wag mutation (0 available); any Col1a1 mutation (166 available)
Rag1tm1Mom mutation (56 available); any Rag1 mutation (132 available)
Tg(KRT5-rtTA)T2D6Sgkd mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
integument phenotype ( J:201145 )
N
• doxycycline-treated mice exhibit normal keratinocyte proliferation and activation
skin lesions ( J:201145 )
• in doxycycline-treated mice but smaller than in mice with wild-type Rag1
skin hyperplasia ( J:201145 )
• in doxycycline-treated mice but less so than in mice with wild-type Rag1

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory