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Phenotypes Associated with This Genotype
Genotype
MGI:5550533
Allelic
Composition		 Plxnd1tm1Ddg/Plxnd1tm1.1Tmj
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129S/SvEv * C57BL/6J * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
Plxnd1tm1.1Tmj mutation (1 available); any Plxnd1 mutation (88 available)
Plxnd1tm1Ddg mutation (0 available); any Plxnd1 mutation (88 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:205528 )
N
• the patterns of hamstring knee flexor muscle and gluteus homonymous monosynaptic sensory-motor connections are similar to controls
abnormal excitatory postsynaptic potential ( J:205528 )
• a large amplitude of monosynaptic EPSP is seen in 45% of gluteus motor neurons unlike in controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory