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Phenotypes Associated with This Genotype
Genotype
MGI:5548193
Allelic
Composition		 Ctdnep1tm3Ryn/Ctdnep1tm3Ryn
Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+
Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctdnep1tm3Ryn mutation (0 available); any Ctdnep1 mutation (18 available)
Gt(ROSA)26Sortm1(EYFP)Cos mutation (24 available); any Gt(ROSA)26Sor mutation (1061 available)
Six2tm1(tTA,tetO-EGFP/cre)Amc mutation (0 available); any Six2 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
decreased kidney apoptosis ( J:205755 )
• apoptotic cells in the nephron as early as P7

cellular
decreased kidney apoptosis ( J:205755 )
• apoptotic cells in the nephron as early as P7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory