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Phenotypes Associated with This Genotype
Genotype
MGI:5546236
Allelic
Composition		 Droshatm1.1Vlcg/Droshatm3Vlcg
Gt(ROSA)26Sortm3.1(cre/ERT2)Vlcg/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Droshatm1.1Vlcg mutation (0 available); any Drosha mutation (98 available)
Droshatm3Vlcg mutation (0 available); any Drosha mutation (98 available)
Gt(ROSA)26Sortm3.1(cre/ERT2)Vlcg mutation (0 available); any Gt(ROSA)26Sor mutation (1061 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:200671 )
N
• tamoxifen-treated mice are born and survive

growth/size/body
decreased body size ( J:200671 )
• tamoxifen-treated mice are runted

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory