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Phenotypes Associated with This Genotype
Genotype
MGI:5544442
Allelic
Composition		 Gt(ROSA)26Sortm3(CAG-EYFP)Hze/Gt(ROSA)26Sor+
Stat5atm2Mam Stat5btm1Mam/Del(11Stat5a-Stat5b)1Mam
Tg(Mx1-cre)1Cgn/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(11Stat5a-Stat5b)1Mam mutation (0 available); any Del(11Stat5a-Stat5b)1Mam mutation (0 available)
Gt(ROSA)26Sortm3(CAG-EYFP)Hze mutation (11 available); any Gt(ROSA)26Sor mutation (1083 available)
Stat5atm2Mam mutation (1 available); any Stat5a mutation (52 available)
Stat5btm1Mam mutation (0 available); any Stat5b mutation (33 available)
Tg(Mx1-cre)1Cgn mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal CD4-positive T cell differentiation ( J:204829 )
• fewer IL9+ cells in IFN-alpha-treated mice following differentiation towards Th9 lineage

immune system
abnormal CD4-positive T cell differentiation ( J:204829 )
• fewer IL9+ cells in IFN-alpha-treated mice following differentiation towards Th9 lineage

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory