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Phenotypes Associated with This Genotype
Genotype
MGI:5543611
Allelic
Composition		 Car2n/Car2n
Car7tm1.1Kkai/Car7tm1.1Kkai
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Car2n mutation (1 available); any Car2 mutation (21 available)
Car7tm1.1Kkai mutation (0 available); any Car7 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal GABA-mediated receptor currents ( J:200079 )
• dendritic GABA-evoked depolarization is smaller in neurons from >P35 compared with wild-type neurons

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory