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Phenotypes Associated with This Genotype
Genotype
MGI:5532706
Allelic
Composition		 Cxcr2tm1Rmra/Cxcr2tm1Rmra
Tg(Mx1-cre)1Cgn/0
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * C57BL/6NTac * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cxcr2tm1Rmra mutation (1 available); any Cxcr2 mutation (32 available)
Tg(Mx1-cre)1Cgn mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal neutrophil physiology ( J:204482 )
• defective ligand scavenging in pIpC treated mice
• decreased migration in sterile peritonitis in pIpC-treated mice

growth/size/body
weight loss ( J:204482 )
• in pIpC treated mice

hematopoietic system
abnormal neutrophil physiology ( J:204482 )
• defective ligand scavenging in pIpC treated mice
• decreased migration in sterile peritonitis in pIpC-treated mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory