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Phenotypes Associated with This Genotype
Genotype
MGI:5526072
Allelic
Composition		 \Mc4rtm1Lowl/\Mc4rtm1Lowl
\Mrap2tm1.1Maj/\Mrap2tm1.1Maj
Genetic
Background		 involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mc4rtm1Lowl mutation (2 available); any Mc4r mutation (46 available)
Mrap2tm1.1Maj mutation (0 available); any Mrap2 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
obese ( J:199365 )
• male double mutants are less obese than male mice homozygous for Mc4rtm1Lowl alone

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory