Phenotypes Associated with This Genotype

Genotype
MGI:5523887

• Allelic Composition: Emx1^{tm1.1(cre)Ito}/Emx1⁺; Scn1a^tm2.1Kzy/Scn1a^tm2.1Kzy; Tg(Slc32a1-cre)65Kzy/0
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:202863 )

• mortality rate before P35 is around 40%, much lower than Scn1a^tm2.1Kzy/+ /Tg(Slc32a1-cre)65Kzy littermates (98%; 40/41)

behavior/neurological

convulsive seizures ( J:202863 )

• mice are normal through week 2 postnatally then develop convulsive seizures in the third week

nervous system

convulsive seizures ( J:202863 )

• mice are normal through week 2 postnatally then develop convulsive seizures in the third week