Phenotypes for Emx1 Scn1a MGI:5523886 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Emx1^{tm1.1(cre)Ito}/Emx1⁺ Scn1a^tm2.1Kzy/Scn1a^tm2.1Kzy
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1^{tm1.1(cre)Ito} mutation (1 available); any Emx1 mutation (31 available)
Scn1a^tm2.1Kzy mutation (1 available); any Scn1a mutation (113 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:202863 )

N	• mice are phsyically normal and do not develop seizures

nervous system

abnormal neocortex morphology ( J:202863 )

• at P21.5, Scn1a immunoreactive neurites oriented toward the pial surface are only occasionally detected relative to control brains, and neurites oriented toward the ventricular surface are not detectable

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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