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Phenotypes Associated with This Genotype
Genotype
MGI:5523693
Allelic
Composition		 Dll1tm1Mjo/Dll1+
Jag1tm1Frad/Jag1tm1Frad
Tg(Six2-EGFP/cre)1Amc/0
Genetic
Background		 involves: 129/Sv * C57BL/6 * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dll1tm1Mjo mutation (4 available); any Dll1 mutation (45 available)
Jag1tm1Frad mutation (0 available); any Jag1 mutation (78 available)
Tg(Six2-EGFP/cre)1Amc mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
absent podocytes ( J:198632 )
• podocytes are almost entirely absent; one allele of Dll1 cannot support podocyte production

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory