Phenotypes for Gt(ROSA)26Sor Tg(MMTV-cre)4Mam MGI:5517429 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^tm1Jus/Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo} Tg(MMTV-cre)4Mam/0
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^tm1Jus mutation (0 available); any Gt(ROSA)26Sor mutation (942 available)
Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo} mutation (10 available); any Gt(ROSA)26Sor mutation (942 available)
Tg(MMTV-cre)4Mam mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

abnormal common lymphocyte progenitor cell morphology ( J:202090 )

• 20-fold increase

increased hematopoietic stem cell number ( J:202090 )

• expanded long term hematopoietic stem-like cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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