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Phenotypes Associated with This Genotype
Genotype
MGI:5516589
Allelic
Composition		 Bmpr2tm1Kmi/Bmpr2+
Ark2cGt(P9-3F)Sor/Ark2c+
Tg(Hlxb9-GFP)1Tmj/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ark2cGt(P9-3F)Sor mutation (0 available); any Ark2c mutation (11 available)
Bmpr2tm1Kmi mutation (0 available); any Bmpr2 mutation (46 available)
Tg(Hlxb9-GFP)1Tmj mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:198828 )
• fewer than expected mice are born
• however, all born mice survive to adulthood

nervous system
abnormal motor neuron innervation pattern ( J:198828 )
• some mice exhibit innervation defects in the dorsal forelimb

behavior/neurological
decreased grip strength ( J:198828 )
• some mice exhibit reduced hang time from a cage lid compared with wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory